BMJ 2000;320:512 ( 19 February )

Letters

Accuracy of perceptions of hepatitis B and C status - Value of screening for hepatitis C is still debatable

Rupert Suckling , specialist registrarKevin Perrett , consultant in communicable disease controlDepartment of Public Health, Rotherham Health Authority, Rotherham S60 3AQ, Mike McKendrick , consultant in infectious diseasesRoyal Hallamshire Hospital, Sheffield S10 2JF

EDITOR - Best et al encourage clinicians to test all injecting drug misusers for hepatitis B and hepatitis C as a "catalyst for further intervention."1 Routine immunisation against hepatitis B in injecting drug misusers is now national policy, and screening for hepatitis B is therefore a sensible first step, but whether to screen for hepatitis C in injecting drug misusers is much more debatable. Best et al have not given their proposal sufficient critical consideration.

When the proposal is examined more critically, serious potential problems are clear. Firstly, it is usually best that an effective and acceptable treatment is available for the condition being screened for. Treatment efficacy itself is only about 40% with dual treatment (which is not currently funded), and the merit of prescribing potentially toxic drugs to patients with disordered lifestyles is unclear. The second potential disadvantage of screening is the probable lack of provision of counselling. Some patients have committed suicide because they were unable to cope with the implications, real or perceived, of the diagnosis. Wider resource implications should also be debated - not least the scale of potential costs. In Sheffield alone there may be around 10 000 injecting drug users. If only half were found to be positive for hepatitis C virus - a very conservative estimate - specialist services would be severely overburdened.

We agree that clinicians must be more vigorous in encouraging drug users to reduce risk behaviours, but screening is not a prerequisite if patients are not suitable for treatment. In view of the potential harms that screening may cause we do not believe, on balance, that clinicians should offer routine screening for hepatitis C until resources for management are available. At the least, a fuller debate is needed nationally and locally before such screening is instituted. The arguments for routine screening will become stronger as more effective treatment emerges, and we welcome the inclusion of dual treatment in the proposed programme of work for the United Kingdom's National Institute for Clinical Effectiveness (NICE).

Rupert Suckling , specialist registrar
rupert.suckling@exs.rotherhm-ha.trent.nhs.uk

Kevin Perrett , consultant in communicable disease control
Department of Public Health, Rotherham Health Authority, Rotherham S60 3AQ

Mike McKendrick , consultant in infectious diseases
Royal Hallamshire Hospital, Sheffield S10 2JF


 

1.

Best D, Noble A, Finch E, Gossop M, Sidwell C, Strang J. Accuracy of perceptions of hepatitis B and C status: cross sectional investigation of opiate addicts in treatment. BMJ 1999; 319: 290-291 [Full Text] . (31 July.)

 

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